The Heidelberg pH Capsule System measures intragastric pH in real time. A swallowed capsule transmits continuous pH to a reader, and a standardized bicarbonate challenge quantifies how the stomach restores its acidity.
SYSTEM COMPONENTSThree pieces capture and read the data, three more are what the protocol runs on.
A single-use capsule that measures intragastric pH and transmits it continuously throughout the test.
An all-in-one unit that receives the capsule's signal and records the pH-versus-time tracing, with a live reading on its own display.
The recording streams into the Acid Tracker software, where the curve, the challenge response, and the full record are reviewed and compared.
Reference standards for the two-point calibration run before every test.
A standardized NaHCO₃ solution that transiently neutralizes gastric acid to provoke reacidification.
A tether holds the capsule in the stomach for the repeat-challenge protocol; removed for free-transit studies.
THE PROTOCOLTwo-point calibration at pH 1.0 and 7.0 against reference buffers.
The tethered capsule is swallowed; fasting baseline pH is recorded, then a standardized bicarbonate challenge raises luminal pH toward neutrality.
Time the return to baseline acidity after each challenge. Repeat in sequence to characterize how strongly the stomach restores its acidity.
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